Erfassung selbst berichteter kardiovaskulärer und metabolischer Erkrankungen in der NAKO Gesundheitsstudie: Methoden und erste Ergebnisse
Lina Jaeschke, Astrid Steinbrecher, Karin Halina Greiser, Marcus Dörr, Thomas Buck, Jakob Linseisen, Christa Meisinger, Wolfgang Ahrens, Heiko Becher, Klaus Berger, Bettina Braun, Hermann Brenner, Stefanie Castell, Beate Fischer, Claus-Werner Franzke, Sylvia Gastell, Kathrin Günther, Wolfgang Hoffmann, Bernd Holleczek, Annika Jagodzinski, Rudolf Kaaks, Alexander Kluttig, Gérard Krause, Lilian Krist, Oliver Kuß, Anna-Therese Lehnich, Michael F. Leitzmann, Wolfgang Lieb, Markus Löffler, Karin B. Michels, Rafael Mikolajczyk, Annette Peters, Tamara Schikowski, Sabine Schipf, Börge Schmidt, Matthias B. Schulze, Henry Völzke, Stefan N. Willich, Tobias Pischon
Abstract
BACKGROUND: Data on self-reported cardiovascular and metabolic diseases are available for the first 100,000 participants of the population-based German National Cohort (GNC, NAKO Gesundheitsstudie). OBJECTIVES: To describe assessment methods and the frequency of self-reported cardiovascular and metabolic diseases in the German National Cohort. MATERIALS AND METHODS: Using a computer-based, standardized personal interview, 101,806 participants (20-75 years, 46% men) from 18 nationwide study centres were asked to use a predefined list to report medical conditions ever diagnosed by a physician, including cardiovascular or metabolic diseases. For the latter, we calculated sex-stratified relative frequencies and compared these with reference data. RESULTS: With regard to cardiovascular diseases, 3.5% of men and 0.8% of women reported to have ever been diagnosed with a myocardial infarction, 4.8% and 1.5% with angina pectoris, 3.5% and 2.5% with heart failure, 10.1% and 10.4% with cardiac arrhythmia, 2.7% and 1.8% with claudicatio intermittens, and 34.6% and 27.0% with arterial hypertension. The frequencies of self-reported diagnosed metabolic diseases were 8.1% and 5.8% for diabetes mellitus, 28.6% and 24.5% for hyperlipidaemia, 7.9% and 2.4% for gout, and 10.1% and 34.3% for thyroid diseases. Observed disease frequencies were lower than reference data for Germany. CONCLUSIONS: In the German National Cohort, self-reported cardiovascular and metabolic diseases diagnosed by a physician are assessed from all participants, therefore representing a data source for future cardio-metabolic research in this cohort.