Litcius/Paper detail

Radioactive nuclei for<i>β</i><sup>+</sup><i>γ</i>PET and theranostics: selected candidates

T. Matulewicz

2021Bio-Algorithms and Med-Systems20 citationsDOIOpen Access PDF

Abstract

Abstract Positron emission tomography (PET) is an established medical diagnostic imaging method. Continuous improvements are aimed at refining image reconstruction, reducing the amount of radioactive tracer and combining with targeted therapy. Time-of-flight (TOF)-PET provides the localization of the tracer through improved time resolution, nuclear physics may contribute to this goal via selection of radioactive nuclei emitting additional γ-rays. This additional radiation, when properly detected, localizes the decay of the tracer at the line of response (LoR) determined by two detected 511 keV quanta. Selected candidates are presented. Some are particularly interesting, as they are strong candidates for theranostic applications.

Topics & Concepts

Pet imagingTRACERRadioactive tracerRadioactive decayPhysicsGamma rayNuclear medicineRadiochemistryMedical physicsNuclear physicsPositron emission tomographyChemistryMedicineRadiopharmaceutical Chemistry and ApplicationsMedical Imaging Techniques and ApplicationsMedical Imaging and Pathology Studies
Radioactive nuclei for<i>β</i><sup>+</sup><i>γ</i>PET and theranostics: selected candidates | Litcius