PD-1 and LAG-3 dual blockade: emerging mechanisms and potential therapeutic prospects in cancer
Xiangyu Qiu, Zhaoan Yu, Xiaoqing Lü, Xin Jin, Jinrong Zhu, Rongxin Zhang
Abstract
The emergence of tumor immunotherapy represents a pivotal milestone in cancer treatment, heralding new hope for cancer patients globally. Immune checkpoint inhibitors have been instrumental in this advance, playing a crucial role in modulating the immune system response to neoplasms. Specifically,
Topics & Concepts
BlockadeMilestoneImmune checkpointCancerImmunotherapyMedicineCancer immunotherapyImmune systemPD-L1OncologyImmunologyInternal medicineHistoryReceptorArchaeologyCancer Immunotherapy and BiomarkersCancer, Stress, Anesthesia, and Immune ResponseFerroptosis and cancer prognosis