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What’s next for cancer vaccines

Juraj Adamik, Lisa H. Butterfield

2022Science Translational Medicine30 citationsDOIOpen Access PDF

Abstract

Cancer vaccines have been shown clinically to drive tumor-reactive cell activation, proliferation, and effector function. Unfortunately, tumor eradication by treatment with cancer vaccines has been unsuccessful in many patients. Critical steps are under way to improve vaccine efficacy and combine them with immunotherapy and standard-of-care treatments.

Topics & Concepts

MedicineCancerCancer immunotherapyEffectorImmunotherapyCancer vaccineImmunologyCancer researchOncologyInternal medicineImmunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkersvaccines and immunoinformatics approaches
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