scRNA-seq reveals ATPIF1 activity in control of T cell antitumor activity
Genshen Zhong, Qi Wang, Ying Wang, Ying Guo, Meiqi Xu, Yaya Guan, Xiaoying Zhang, Minna Wu, Zhishan Xu, Weidong Zhao, Hongkai Lian, Hui Wang, Jianping Ye
Abstract
T cells in cancer immunotherapy. Induction of ATPIF1 activity may promote CAR-T activity in cancer therapy.
Topics & Concepts
Immune systemCD8T cellBiologyCancer researchCytotoxic T cellTumor microenvironmentMelanomaImmunologyBiochemistryIn vitroCAR-T cell therapy researchCancer Immunotherapy and BiomarkersAdenosine and Purinergic Signaling