A nano-composite based regenerative neuro biosensor sensitive to Parkinsonism-associated protein DJ-1/Park7 in cerebrospinal fluid and saliva
Münteha Nur Sonuç Karaboğa, Mustafa Kemal Sezgintürk
Abstract
. Since changes in the expression of DJ-1 protein is particularly important in cerebrospinal fluid (CSF) and saliva, the ability of the developed neurobiosensor system to detect the DJ-1 protein in these media was tested by the standard addition method. The statistical results show that the biosensor decorated with MWCNT-AuNP-AUT may be recommended for the selective determination of DJ-1 protein.
Topics & Concepts
Dielectric spectroscopyCyclic voltammetryElectrodeDetection limitMaterials scienceBiosensorCarbon nanotubeSalivaChemistryChromatographyNanotechnologyElectrochemistryBiochemistryPhysical chemistryConducting polymers and applicationsElectrochemical sensors and biosensorsParkinson's Disease Mechanisms and Treatments