Litcius/Paper detail

Novel anatomical guidelines for botulinum neurotoxin injection in the mentalis muscle: a review

Kyu‐Ho Yi, Ji‐Hyun Lee, Hyewon Hu, Hyun-Jun Park, Hyungkyu Bae, Kang‐Woo Lee, Hee‐Jin Kim

2023Anatomy & Cell Biology28 citationsDOIOpen Access PDF

Abstract

The mentalis muscle is a paired muscle originating from the alveolar bone of the mandible. This muscle is the main target muscle for botulinum neurotoxin (BoNT) injection therapy, which aims to treat cobblestone chin caused by mentalis hyperactivity. However, a lack of knowledge on the anatomy of the mentalis muscle and the properties of BoNT can lead to side effects, such as mouth closure insufficiency and smile asymmetry due to ptosis of the lower lip after BoNT injection procedures. Therefore, we have reviewed the anatomical properties associated with BoNT injection into the mentalis muscle. An up-to-date understanding of the localization of the BoNT injection point according to mandibular anatomy leads to better injection localization into the mentalis muscle. Optimal injection sites have been provided for the mentalis muscle and a proper injection technique has been described. We have suggested optimal injection sites based on the external anatomical landmarks of the mandible. The aim of these guidelines is to maximize the effects of BoNT therapy by minimizing the deleterious effects, which can be very useful in clinical settings.

Topics & Concepts

MedicineChinMandible (arthropod mouthpart)PtosisAnatomySurgeryBiologyGenusBotanyBotulinum Toxin and Related Neurological DisordersFacial Rejuvenation and Surgery TechniquesNeurological disorders and treatments