ACSL4 and the lipoxygenases 15/15B are pivotal for ferroptosis induced by iron and PUFA dyshomeostasis in dopaminergic neurons
Hind Bouchaoui, Laura Mahoney‐Sanchez, Guillaume Garçon, Olivier Berdeaux, L. Alleman, David Devos, James A. Duce, Jean-Christophe Devedjian
Topics & Concepts
Programmed cell deathDopaminergicLipid peroxidationNeuroprotectionArachidonic acidChemistryGPX4Polyunsaturated fatty acidCell biologyPharmacologyBiochemistryBiologyNeuroscienceOxidative stressDopamineFatty acidApoptosisSuperoxide dismutaseEnzymeGlutathione peroxidaseFerroptosis and cancer prognosisCholesterol and Lipid MetabolismCancer-related molecular mechanisms research