miR-27a-3p Targets ATF3 to Reduce Calcium Deposition in Vascular Smooth Muscle Cells
Nakwon Choe, Duk‐Hwa Kwon, Juhee Ryu, Sera Shin, Hye Jung Cho, Hosouk Joung, Gwang Hyeon Eom, Youngkeun Ahn, Woo Jin Park, Kwang Il Nam, Young‐Kook Kim, Hyun Kook
Abstract
may contribute to the development of vascular calcification by de-repression of ATF3.
Topics & Concepts
Vascular smooth muscleActivating transcription factormicroRNAATF3CalcificationEctopic calcificationBiologyDownregulation and upregulationTranscription factorEctopic expressionCalciumCell biologyMessenger RNAEndocrinologyInternal medicineChemistryMedicineGene expressionPromoterBiochemistryGeneSmooth muscleMicroRNA in disease regulationCircular RNAs in diseasesRNA modifications and cancer