An acid-responsive MOF nanomedicine for augmented anti-tumor immunotherapy via a metal ion interference-mediated pyroptotic pathway
Zhenzhen Feng, Gui Chen, Min Zhong, Ling Lin, Ziyi Mai, Yan Tang, Guimei Chen, Wen Ma, Guang Li, Yuanyuan Yang, Zhiqiang Yu, Meng Yu
Topics & Concepts
PyroptosisTumor microenvironmentImmune systemImmunotherapyCancer researchImmunogenic cell deathProinflammatory cytokineProgrammed cell deathAdjuvantMaterials scienceInflammationMedicineImmunologyChemistryApoptosisBiochemistryInflammasome and immune disordersHeme Oxygenase-1 and Carbon MonoxideExtracellular vesicles in disease