Clonally expanded memory CD8+ T cells accumulate in atherosclerotic plaques and are pro-atherogenic in aged mice
Daniel J. Tyrrell, Kathleen M. Wragg, Judy Chen, Hui Wang, Jianrui Song, Muriel G. Blin, Chase Bolding, Donald Vardaman, Kara Giles, Harrison Tidwell, Md Akkas Ali, Abhinav Janappareddi, Sherri C. Wood, Daniel R. Goldstein
Topics & Concepts
Cytotoxic T cellGranzyme BCD8BiologyAdoptive cell transferImmunologyImmune systemGranzymeT cellEffectorCell biologyPerforinIn vitroGeneticsAtherosclerosis and Cardiovascular DiseasesT-cell and B-cell ImmunologySingle-cell and spatial transcriptomics