Effectiveness of Low-dose Ethinylestradiol/Cyproterone Acetate and Ethinylestradiol/Desogestrel with and without Metformin on Hirsutism in Polycystic Ovary Syndrome: A Randomized, Double-blind, Triple-dummy Study.
Sanjeewani Fonseka, Chandrika Wijeyaratne, Indika Gawarammana, Nishan S. Kalupahana, Shanthini Rosairo, Neelakanthi Ratnatunga, Ranjith Kumarasiri
Abstract
EE/CPA and EE/DES were equally effective in improving hirsutism in PCOS, with no added benefit from low-dose metformin. Sri Lanka Clinical Trials Registry (http://www.slctr.lk) registration no. SLCTR/2015/007.
Topics & Concepts
MedicinehirsutismEthinylestradiolPolycystic ovaryCyproterone acetateDesogestrelCyproteroneMetforminInternal medicineAntiandrogenGynecologyEndocrinologyUrologyAndrogenPopulationInsulinFamily planningHormoneInsulin resistanceEnvironmental healthResearch methodologyOvarian function and disordersReproductive Biology and FertilitySexual function and dysfunction studies