Three-dimensional printed biodegradable poly(l-lactic acid)/(poly(d-lactic acid) scaffold as an intervention of biomedical substitute
Mohamad Amin Jumat, Pascale Chevallier, Diego Mantovani, Francesco Copes, Saiful Izwan Abd Razak, Syafiqah Saidin
Abstract
In biomedical application, the fabrication of biodegradable scaffolds using 3D printing technology has vastly increased to accommodate the complex structure of substitutes. In this study, PLLA and PDLA were hot-melt extruded for the 3D printing of PLLA/PDLA scaffolds. The incorporation of PDLA into the PLLA has enhanced the hydrophobicity and mechanical properties of the scaffolds. The degraded PLLA/PDLA scaffolds were observed to retain its chemical functionalities. Less crack formation, less acidity of the degraded solution, higher percentages of remaining weight, greater average molecular weight, and higher crystallinity percentages were recorded on the higher PDLA composition after the degradation analysis.