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Construction and transformations of 2,2-difluoro-2,3-dihydrofurans from enaminones and diflurocarbene

Heyun Sheng, Zhiwei Chen, Xue Li, Jianke Su, Qiuling Song

2022Organic Chemistry Frontiers38 citationsDOI

Abstract

A simple and efficient construction of 2-difluoro-2,3-dihydrofurans is reported, which features metal-free and additive-free conditions, high functional group tolerance and readily accessible starting materials.

Topics & Concepts

ChemistrySimple (philosophy)Functional groupCombinatorial chemistryOrganic chemistryEpistemologyPolymerPhilosophyFluorine in Organic ChemistryCyclopropane Reaction MechanismsSynthesis and Reactions of Organic Compounds
Construction and transformations of 2,2-difluoro-2,3-dihydrofurans from enaminones and diflurocarbene | Litcius