AbaM Regulates Quorum Sensing, Biofilm Formation, and Virulence in <i>Acinetobacter baumannii</i>
Mario López-Martín, Jean‐Frédéric Dubern, Morgan R. Alexander, Paul Williams
Abstract
increased AHL production, surface motility, and biofilm development, it resulted in the attenuation of virulence. AbaM was found to control both QS-dependent and QS-independent genes. The significance of this work lies in the identification of AbaM, an RsaM ortholog known to control virulence in plant pathogens, as a modulator of virulence in a human pathogen.
Topics & Concepts
BiologyAcinetobacter baumanniiQuorum sensingBiofilmVirulenceMicrobiologyBacterial proteinAcinetobacterBacteriaPseudomonas aeruginosaGeneGeneticsAntibioticsAntibiotic Resistance in BacteriaVibrio bacteria research studiesBacterial biofilms and quorum sensing