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Dynamic changes in the gut microbiota play a critical role in age-associated cognitive dysfunction via SCFAs and LPS synthesis metabolic pathways during brain aging

Xiaoying Ma, Jiaying Liu, Lei Jiang, Zhaoyu Gao, Zhongli Shi, Nan Zhang, Zhen Wang, Shujin Li, Rui Zhang, Shunjiang Xu

2025International Journal of Biological Macromolecules14 citationsDOI

Topics & Concepts

Gut floraCognitionCognitive agingBrain agingNeuroscienceAging brainGut–brain axisMetabolic pathwayCognitive declineBiologyPsychologyGerontologyComputational biologyMedicineMetabolismImmunologyBiochemistryDementiaInternal medicineDiseaseGut microbiota and healthBarrier Structure and Function StudiesClostridium difficile and Clostridium perfringens research
Dynamic changes in the gut microbiota play a critical role in age-associated cognitive dysfunction via SCFAs and LPS synthesis metabolic pathways during brain aging | Litcius