Litcius/Paper detail

A p97/Valosin-Containing Protein Inhibitor Drug CB-5083 Has a Potent but Reversible Off-Target Effect on Phosphodiesterase-6

Henri Leinonen, Cheng Cheng, Marja Pitkänen, Christopher L. Sander, Jianye Zhang, Sama Saeid, Teemu Turunen, Alyaa Shmara, Lan Weiss, Lac Ta, Timothy Ton, Ari Koskelainen, Jesse D. Vargas, Virginia Kimonis, Krzysztof Palczewski

2021Journal of Pharmacology and Experimental Therapeutics47 citationsDOIOpen Access PDF

Topics & Concepts

VardenafilMedicinePharmacologyIn vivoEx vivoElectroretinographyInternal medicineSildenafilRetinalBiologyTadalafilOphthalmologyBiotechnologyRetinal Development and DisordersDrug-Induced Ocular ToxicityRetinal Diseases and Treatments