Real-world effectiveness of monkeypox vaccines: a systematic review
Mingda Xu, Caifen Liu, Zhanwei Du, Yuan Bai, Zhen Wang, Chao Gao
Abstract
A systematic review was conducted to investigate and understand the real-world effectiveness of smallpox vaccines against mpox during 2022 outbreaks. The effectiveness of MVA-BN was estimated to be 87% [95% confidence interval (CI): 84–90%] for one-dose and 89% (95% CI: 78–100%) for two-dose vaccination. The next-generation vaccines are recommended for future preparedness.
Topics & Concepts
MedicineMonkeypoxSmallpoxConfidence intervalVaccinationVirologySmallpox vaccinePreparednessOutbreakInternal medicineVacciniaChemistryRecombinant DNAPolitical scienceBiochemistryLawGenePoxvirus research and outbreaksBacillus and Francisella bacterial researchHerpesvirus Infections and Treatments