Loss of function polymorphisms in SLCO1B1 (c.521T>C, rs4149056) and ABCG2 (c.421C>A, rs2231142) genes are associated with adverse events of rosuvastatin: a case–control study

Iveta Merćep, Ivana Radman, Vladimir Trkulja, Tamara Božina, Livija Šimičević, Ema Budimir, Lana Ganoci, Nada Božina

2021European Journal of Clinical Pharmacology22 citationsDOI

Topics & Concepts

SLCO1B1RosuvastatinMedicinePharmacogeneticsPharmacologyCYP2C9CYP2C19Internal medicineOdds ratioGenotypeBiologyCytochrome P450GeneticsGeneMetabolismDrug Transport and Resistance MechanismsDrug-Induced Hepatotoxicity and ProtectionCholesterol and Lipid Metabolism

Loss of function polymorphisms in SLCO1B1 (c.521T&gt;C, rs4149056) and ABCG2 (c.421C&gt;A, rs2231142) genes are associated with adverse events of rosuvastatin: a case–control study

Topics & Concepts

Loss of function polymorphisms in SLCO1B1 (c.521T>C, rs4149056) and ABCG2 (c.421C>A, rs2231142) genes are associated with adverse events of rosuvastatin: a case–control study