NOX2-derived hydrogen peroxide impedes the AMPK/Akt-mTOR signaling pathway contributing to cell death in neuronal cells
Ruijie Zhang, Chunxiao Liu, Yang Liu, Tong Ji, Nana Zhang, Xiaoqing Dong, Xin Chen, Jing Ma, Wei Gao, Shile Huang, Long Chen
Topics & Concepts
ApocyninProtein kinase BPI3K/AKT/mTOR pathwayAMPKNADPH oxidaseCell biologyChemistrySignal transductionReactive oxygen speciesOxidative stressApoptosisBiologyProtein kinase ABiochemistryPhosphorylationParkinson's Disease Mechanisms and TreatmentsNeutrophil, Myeloperoxidase and Oxidative MechanismsAdvanced Glycation End Products research