Variants of the adeno-associated virus serotype 9 with enhanced penetration of the blood–brain barrier in rodents and primates
Yizheng Yao, Jun Wang, Yi Liu, Yuan Qu, Kaikai Wang, Yang Zhang, Yuxin Chang, Zhi Yang, Jie Wan, Junfeng Liu, Hiroshi Nakashima, Sean Lawler, E. Antonio Chiocca, Choi‐Fong Cho, Fengfeng Bei
Topics & Concepts
Adeno-associated virusTranscytosisTransduction (biophysics)Central nervous systemCapsidBiologyBlood–brain barrierGene deliveryVirologyNervous systemGenetic enhancementVirusCell biologyCellGeneNeuroscienceVector (molecular biology)GeneticsEndocytosisBiochemistryRecombinant DNAVirus-based gene therapy researchRNA Interference and Gene DeliveryRNA regulation and disease