Knockdown of lncRNA PVT1 attenuated macrophage M1 polarization and relieved sepsis induced myocardial injury via miR-29a/HMGB1 axis
Yuanyuan Luo, Zhongqi Yang, Xinfeng Lin, Fengli Zhao, Haitao Tu, Lingjun Wang, Minyong Wen, Shaoxiang Xian
Topics & Concepts
PVT1Gene knockdownMacrophage polarizationSepsisHMGB1MacrophageIn vivoChemistryDownregulation and upregulationBlotMyocarditisMedicineInflammationCancer researchCell biologyImmunologyBiologyInternal medicineIn vitroLong non-coding RNABiochemistryApoptosisGeneBiotechnologyCancer-related molecular mechanisms researchImmune cells in cancerImmune Response and Inflammation