A Translational Study of a Silicon Phthalocyanine Substituted with a Histone Deacetylase Inhibitor for Photodynamic Therapy
Başak Aru, Aysel Günay, Elif Şenkuytu, Gülderen Yanıkkaya Demirel, Ayşe Gül Gürek, Devrim Atílla
Abstract
. Our further studies will be conducted with primary breast cancer cell culture to give a better insight into the anticancer mechanism of the compound.
Topics & Concepts
Histone deacetylase inhibitorSinglet oxygenHistone deacetylaseCancer researchChemistryPhotodynamic therapyAcetylationApoptosisCell cultureCell cycleCancer cellCancerHistoneMedicineBiochemistryBiologyInternal medicineOxygenDNAOrganic chemistryGeneGeneticsHistone Deacetylase Inhibitors ResearchPhotodynamic Therapy Research StudiesClick Chemistry and Applications