Discovery and development of novel pyrimidine and pyrazolo/thieno-fused pyrimidine derivatives as potent and orally active inducible nitric oxide synthase dimerization inhibitor with efficacy for arthritis

Liu Zeng Chen, Hai Shu, Jing Wu, Yun Long Yu, Duo Ma, Xin Huang, Ming Ming Liu, Xin Hua Liu, Jing Bo Shi