NASP modulates histone turnover to drive PARP inhibitor resistance
Sarah C. Moser, Anna Khalizieva, Josef Roehsner, Elisabeth Pottendorfer, Milo L. Kaptein, Giulia Ricci, Vivek Bhardwaj, Onno B. Bleijerveld, Liesbeth Hoekman, Ingrid van der Heijden, Simone Di Sanzo, Alexander Fish, Aleksandra Chikunova, Judith H.I. Haarhuis, Roel Oldenkamp, Luisa Robbez‐Masson, Justin Sprengers, Daniël J. Vis, Lodewyk F.A. Wessels, Marieke van de Ven, Stephen J. Pettitt, Andrew Tutt, Christopher J. Lord, Benjamin D. Rowland, Moritz Völker-Albert, Francesca Mattiroli, Thijn R. Brummelkamp, Abdelghani Mazouzi, Jos Jonkers
Topics & Concepts
PARP inhibitorHistoneChemistryCell biologyPoly ADP ribose polymeraseBiologyBiochemistryDNAPolymerasePARP inhibition in cancer therapyDNA Repair MechanismsCRISPR and Genetic Engineering