A green and chemoselective synthesis of coumarins via Pechmann condensation using recoverable heterogeneous catalyst (Au@pSiO<sub>2</sub>)
Mandana Yaghoobi, Daryoush Zareyee, Mohammad A. Khalilzadeh
Abstract
Nano Au@porous SiO 2 as a heterogeneous catalyst was prepared and characterized by Fourier transform infrared, X‐ray powder diffraction, transmission electron microscopy, thermogravimetric analysis and inductively coupled plasma–atomic emission spectroscopy techniques and then used as an efficient catalyst in the condensation of various phenols with ethyl acetoacetate for the preparation of coumarin derivatives through the Pechmann reaction. The combined merits of chemoselective and solvent free reaction conditions and the recyclability of the nanostructured catalyst make the condensation a safe operation, with low pollution, rapid access to products and simple workup.
Topics & Concepts
ChemistryCatalysisEthyl acetoacetatePhenolsThermogravimetric analysisCondensationHeterogeneous catalysisOrganic chemistryInductively coupled plasma atomic emission spectroscopyCondensation reactionFourier transform infrared spectroscopyInductively coupled plasmaGreen chemistryChemical engineeringReaction mechanismQuantum mechanicsPlasmaEngineeringThermodynamicsPhysicsMulticomponent Synthesis of HeterocyclesNanomaterials for catalytic reactionsAdvanced Nanomaterials in Catalysis