Intracellular connections between basal bodies promote the coordinated behavior of motile cilia
Adam W. J. Soh, Louis G. Woodhams, Anthony D. Junker, Cassidy M. Enloe, Benjamin E. Noren, Adam Harned, Christopher J. Westlake, Kedar Narayan, John Oakey, Philip V. Bayly, Chad G. Pearson
Abstract
Whether intracellular connections between basal bodies control ciliary behavior in multiciliated cells is investigated. Using a Tetrahymena live cell immobilization technique to quantify ciliary dynamics, it is shown that inter-BB connections are required for effective ciliary waveform and coordinated ciliary beating that promote fluid flow.
Topics & Concepts
CiliumBasal bodyMotile ciliumBiologyCell biologyTetrahymenaMotilityMicrotubuleCell cortexCytoskeletonVideo microscopyAnatomyBiophysicsFlagellumCellGeneticsGeneMicro and Nano RoboticsProtist diversity and phylogenyMicrotubule and mitosis dynamics