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TRIM40 inhibits IgA1-induced proliferation of glomerular mesangial cells by inactivating NLRP3 inflammasome through ubiquitination

Jiaojiao Shen, WU Qing, Tingyu Liang, Jian Zhang, Jia-Yuan Bai, Meijie Yuan, Peicheng Shen

2021Molecular Immunology31 citationsDOI

Topics & Concepts

InflammasomeUbiquitinNephropathyCell biologyGlomerulonephritisImmunologyInnate immune systemMesangial cellPathogenesisInflammationChemistryBiologyCancer researchIn vitroImmune systemKidneyEndocrinologyBiochemistryDiabetes mellitusGeneInflammasome and immune disordersRenal Diseases and GlomerulopathiesAutoimmune and Inflammatory Disorders Research
TRIM40 inhibits IgA1-induced proliferation of glomerular mesangial cells by inactivating NLRP3 inflammasome through ubiquitination | Litcius