Intramolecular charge transfer enhancing strategy based MAO-A specific two-photon fluorescent probes for glioma cell/tissue imaging
Haixiao Fang, Riri Shi, Ding Chen, Yunwei Qu, Qiong Wu, Xuekang Yang, Xiaomei Lü, Chengwu Zhang, Lin Li, Kah‐Leong Lim
Abstract
Picking MAO-A: a new ICT-based two-photon small molecule fluorescent probe (A3), successfully detected endogenous MAO-A activity from a variety of biological samples, including live mammalian cells and human glioma tissue.
Topics & Concepts
FluorescenceIntramolecular forceGliomaTwo-photon excitation microscopyFluorescence microscopeBiophysicsChemistryFluorescence-lifetime imaging microscopyEndogenyCellMicroscopyCancer researchBiologyBiochemistryPathologyStereochemistryOpticsMedicinePhysicsNanoplatforms for cancer theranosticsPhotochromic and Fluorescence ChemistryAnalytical Chemistry and Sensors