Recombinase-mediated cassette exchange-based screening of a CRISPR/Cas9 library for enhanced recombinant protein production in human embryonic kidney cells: Improving resistance to hyperosmotic stress
Seunghyeon Shin, Su Hyun Kim, Jong-Ho Park, Jae Seong Lee, Gyun Min Lee
Topics & Concepts
CRISPRHEK 293 cellsBiologyCas9Embryonic stem cellOsmotic shockCell biologyGenome editingRecombinaseGeneComputational biologyGeneticsRecombinationCRISPR and Genetic EngineeringPluripotent Stem Cells ResearchAnimal Genetics and Reproduction