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Association of BMI With Benefit of Metformin Plus Epidermal Growth Factor Receptor–Tyrosine Kinase Inhibitors in Patients With Advanced Lung Adenocarcinoma

Óscar Arrieta, Zyanya Lucía Zatarain-Barrón, Jenny G. Turcott, Feliciano Barrón, Sai Yendamuri, Andrés F. Cardona, Rafael Rosell

2022JAMA Oncology24 citationsDOIOpen Access PDF

Abstract

This secondary analysis reports the survival outcome in patients with EGFR variant-positive non–small-cell lung cancer who had a body mass index that was higher or lower than 24.

Topics & Concepts

MedicineMetforminEpidermal growth factor receptorInternal medicineTyrosine kinaseAdenocarcinomaOncologyLung cancerLungAdenocarcinoma of the lungRandomized controlled trialCancer researchCancerReceptorInsulinGastric Cancer Management and OutcomesLung Cancer Treatments and MutationsMetabolism, Diabetes, and Cancer
Association of BMI With Benefit of Metformin Plus Epidermal Growth Factor Receptor–Tyrosine Kinase Inhibitors in Patients With Advanced Lung Adenocarcinoma | Litcius