Suppressive role of microRNA-130b-3p in ferroptosis in melanoma cells correlates with DKK1 inhibition and Nrf2-HO-1 pathway activation
Yangying Liao, Xiaomin Jia, Yi Ren, Zhuoga Deji, Yuzhen Gesang, Ning Ning, Hao Feng, Hong Yu, Wei An
Topics & Concepts
DKK1ChemistryHeme oxygenaseMelanomaDownregulation and upregulationViability assaymicroRNACancer researchLipid peroxidationWestern blotCell biologyBiologyMolecular biologyCellSignal transductionHemeBiochemistryOxidative stressGeneWnt signaling pathwayEnzymeFerroptosis and cancer prognosisCancer-related molecular mechanisms researchRNA modifications and cancer