Hair shaft miniaturization causes stem cell depletion through mechanosensory signals mediated by a Piezo1-calcium-TNF-α axis
Yuhua Xie, Daoming Chen, Kaiju Jiang, Lifang Song, Nannan Qian, Yingxue Du, Yong Yang, Fengchao Wang, Ting Chen
Topics & Concepts
BiologyPIEZO1MiniaturizationCell biologyCalciumStem cellTumor necrosis factor alphaMechanotransductionInternal medicineImmunologyBiochemistryElectrical engineeringReceptorEngineeringMedicineMechanosensitive channelsIon channelHair Growth and DisordersSkin and Cellular Biology ResearchWnt/β-catenin signaling in development and cancer