Low-cost potentiometric paper-based analytical device based on newly synthesized macrocyclic pyrido-pentapeptide derivatives as novel ionophores for point-of-care copper(<scp>ii</scp>) determination
Ayman H. Kamel, Abd El‐Galil E. Amr, Abdulrahman A. Almehizia, Elsayed Ahmed Elsayed, Gaber O. Moustafa
Abstract
detection in real samples of serum and whole blood collected from different children with autism spectrum disorder. The data obtained by the proposed potentiometric method were compared with those obtained by the inductively-coupled plasma (ICP) as a reference method. The presented copper paper-based analytical-device can be considered as an attractive tool for point-of-care copper determination because of its affordability, vast availability, and self-pumping ability, particularly when combined with potentiometric detection.
Topics & Concepts
Potentiometric titrationPentapeptide repeatCopperChemistryCombinatorial chemistryPoint of careChromatographyOrganic chemistryIonBiochemistryMedicineNursingPeptideAnalytical Chemistry and SensorsElectrochemical sensors and biosensorsBiosensors and Analytical Detection