Enantioselective Copper-Catalyzed Synthesis of Trifluoromethyl-Cyclopropylboronates
Julia Altarejos, David Sucunza, Juan J. Vaquero, Javier Carreras
Abstract
-2-arylcyclopropylamines, which are prevalent motifs in biologically active compounds.
Topics & Concepts
CyclopropanationChemistryEnantioselective synthesisTrifluoromethylCatalysisCombinatorial chemistryCopperTransformation (genetics)Formal synthesisOrganic chemistryStereochemistryStereoisomerismBiochemistryAlkylGeneFluorine in Organic ChemistryCyclopropane Reaction MechanismsN-Heterocyclic Carbenes in Organic and Inorganic Chemistry