Photocatalytic Alkynylation of Hydrosilanes via Hydrogen Atom Transfer
Xinhan Li, Fuqin Zhang, Yao Zhong, Na Li, Jianbin Xu, Baomin Fan
Abstract
Alkynylsilanes are significant structural units frequently used in synthetic chemistry, medicinal chemistry, functional materials, and life sciences. Herein, we report a method for using a hydrogen atom transfer (HAT) strategy in combination with visible-light-driven photocatalysis to achieve a direct coupling reaction between benzene sulfonyl acetylene and tertiary silanes, and a diverse alkynylation of hydrosilanes in the presence of reactive groups was achieved with this strategy. It is important to note that dihydroalkyl/aryl silanes are also suitable for the protocol of HAT photocatalytic of 4CzIPN and quinuclidine.
Topics & Concepts
SilanesPhotocatalysisAlkynylationChemistrySulfonylPhotochemistryHydrogen atomArylCatalysisBenzeneAcetyleneCombinatorial chemistryOrganic chemistryGroup (periodic table)AlkylSilaneRadical Photochemical ReactionsSulfur-Based Synthesis TechniquesCatalytic C–H Functionalization Methods