A covalent organic framework-derived M1 macrophage mimic nanozyme for precise tumor-targeted imaging and NIR-II photothermal catalytic chemotherapy
Peng Gao, Kaixian Wang, Ruyue Wei, Xiaoying Shen, Wei Pan, Na Li, Bo Tang
Abstract
into toxic ˙OH that synergized with its NIR-II photothermal effect to strengthen the chemotherapy. Therefore, highly efficient tumor-targeted imaging and NIR-II PTCEC were realized with an M1 macrophage mimic nanoprobe. This work provides a feasible tactic for a biomimetic theranostic nanoprobe and will inspire the development of new bioactive nanomaterials for clinical tumor theranostic applications.
Topics & Concepts
Photothermal therapyChemistryCovalent bondMacrophageChemotherapyCatalysisNanotechnologyCancer researchBiophysicsMaterials scienceMedicineBiochemistryBiologyOrganic chemistrySurgeryIn vitroNanoplatforms for cancer theranosticsAdvanced Nanomaterials in CatalysisMetal-Organic Frameworks: Synthesis and Applications