Long‐term extension study of tofacitinib in refractory dermatomyositis
Julie J. Paik, Matthew Shneyderman, Laura Gutierrez‐Alamillo, Jemima Albayda, Eleni Tiniakou, Jamie Perin, Grazyna Purwin, Sherry Leung, Doris G. Leung, Livia Casciola‐Rosen, Andrew Koenig, Lisa Christopher‐Stine
Abstract
We previously demonstrated that tofacitinib was effective in treating skin-predominant refractory dermatomyositis (DM) at 12 weeks in a prospective open label clinical trial, Study of Tofacitinib In Refractory dermatomyositis (STIR) (1). Here, we report the long-term extension results of up to 96 weeks to investigate the treatment durability of tofacitinib in refractory DM. Inclusion criteria and outcome measures were the same as the parent study (1). Assessments were conducted at weeks 20, 72, and 96. The baseline demographic features of all 10 trial patients were reported previously (1).