Activated T cell-derived exosomes for targeted delivery of AXL-siRNA loaded paclitaxel-poly-L-lysine prodrug to overcome drug resistance in triple-negative breast cancer
Chuanrong Chen, Ming Shen, Xiaofeng Wan, Lili Sheng, Yang He, Menglin Xu, Meng Yuan, Zhaoning Ji, Jiali Zhang
Topics & Concepts
Cancer researchPaclitaxelTriple-negative breast cancerTumor microenvironmentMicrovesiclesImmune systemProdrugChemistryChemoimmunotherapyImmunotherapyBiologyPharmacologyCancerImmunologyMedicineBreast cancerBiochemistryInternal medicinemicroRNAGeneImmunotherapy and Immune ResponsesPhagocytosis and Immune RegulationCancer Immunotherapy and Biomarkers