Magnetism-mediated targeting hyperthermia-immunotherapy in “cold” tumor with CSF1R inhibitor
Yuefei Fang, Yang He, Canhao Wu, Meng Zhang, Zeyun Gu, Jiaxin Zhang, Ergang Liu, Qin Xu, Akmal M. Asrorov, Yongzhuo Huang
Abstract
This work demonstrated that TAT-BLZmlips with magnetic navigation and MHT can remodel tumor microenvironment and activate immune responses and memory, thus inhibiting tumor growth and recurrence.
Topics & Concepts
HyperthermiaImmunotherapyMagnetismCancer researchMedicineChemistryImmunologyImmune systemInternal medicinePhysicsQuantum mechanicsCancer, Hypoxia, and MetabolismNanoplatforms for cancer theranosticsImmune cells in cancer