A fast responsive and cell membrane-targetable near-infrared H<sub>2</sub>S fluorescent probe for drug resistance bioassays in chemotherapy
Yifan He, Wei Hu, Li Chai, Yanying Wang, Xian Wang, Tao Liang, Haiyan Li, Chunya Li
Abstract
. This probe exhibited high selectivity and an extremely fast response rate. Cell imaging results demonstrated that there was a close relationship between the overexpression of NFS1 and drug resistance and inhibition of NFS1 was beneficial for improving the efficacy of chemotherapy.
Topics & Concepts
FluorescenceMembraneCellChemistryBiophysicsSelectivityCell membraneDrugDrug resistanceChemotherapyBiochemistryPharmacologyMedicineBiologyMicrobiologySurgeryCatalysisQuantum mechanicsPhysicsSulfur Compounds in BiologyNanoplatforms for cancer theranosticsMolecular Sensors and Ion Detection