Immortalized human choroid plexus endothelial cells enable an advanced endothelial-epithelial two-cell type in vitro model of the choroid plexus
Walter Muranyi, Christian Schwerk, Rosanna Herold, Carolin Stump-Guthier, Marko Lampe, Petra Fallier‐Becker, Christel Weiß, Carsten Sticht, Hiroshi Ishikawa, Horst Schroten
Abstract
model with a consistently enhanced barrier function specifically by iHCPEnC. Overall, iHCPEnC present a tool that will contribute to the understanding of CP organ functions, especially endothelial-epithelial interplay.
Topics & Concepts
Choroid plexusCell biologyMatrigelEndothelial stem cellBiologyImmortalised cell lineEndotheliumIn vitroCell cultureTelomerase reverse transcriptaseEpitheliumUmbilical veinAnatomyTelomeraseCentral nervous systemBiochemistryEndocrinologyGeneGeneticsBarrier Structure and Function StudiesMicroRNA in disease regulationNeurogenesis and neuroplasticity mechanisms