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Potential Prebiotic Properties of Whey Protein and Glycomacropeptide in Gut Microbiome

Bryna Rackerby, Hoang Ngoc M. Le, Avery Haymowicz, David C. Dallas, Si Hong Park

2024Food Science of Animal Resources19 citationsDOIOpen Access PDF

Abstract

Proteins in whey have prebiotic and antimicrobial properties. Whey protein comprises numerous bioactive proteins and peptides, including glycomacropeptide (GMP), a hydrophilic casein peptide that separates with the whey fraction during cheese making. GMP has traditionally been used as a protein source for individuals with phenylketonuria and also has prebiotic (supporting the growth of Bifidobacterium and lactic acid bacteria) and antimicrobial activities. GMP supplementation may help positively modulate the gut microbiome, help treat dysbiosis-related gastrointestinal disorders and improve overall health in consumers.

Topics & Concepts

PrebioticGut microbiomeMicrobiomeFood scienceChemistryBiologyBioinformaticsMicrobial Metabolites in Food BiotechnologyInfant Nutrition and HealthFood composition and properties
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