Palladium-catalyzed C–H bond activation for the assembly of <i>N</i>-aryl carbazoles with aromatic amines as nitrogen sources
Xiaobing Liu, Heyun Sheng, Yao Zhou, Qiuling Song
Abstract
A convenient and efficient palladium-catalyzed C-H bond activation for the assembly of N-aryl carbazole is reported, in which two C-N bonds were formed under one set of conditions. The desired carbazoles were achieved in decent yields with a wide substrate scope by utilizing readily available 2-iodo biphenyls and aromatic amines as starting materials.
Topics & Concepts
PalladiumCatalysisArylChemistryNitrogenMedicinal chemistryOrganic chemistryPolymer chemistryPhotochemistryAlkylCatalytic C–H Functionalization MethodsCatalytic Cross-Coupling ReactionsRadical Photochemical Reactions