Diltiazem potentiates the cytotoxicity of gemcitabine and 5-fluorouracil in PANC-1 human pancreatic cancer cells through inhibition of P-glycoprotein
Hesham A. El‐Mahdy, Ahmed A. El-Husseiny, Yasser I. Kandil, Ayman M. Gamal El-Din
Topics & Concepts
GemcitabineDiltiazemPancreatic cancerApoptosisPharmacologyViability assayCancer researchChemistryMTT assayCytotoxicityMedicineInternal medicineCancerBiochemistryIn vitroCalciumDrug Transport and Resistance MechanismsCancer, Stress, Anesthesia, and Immune ResponseProtein Kinase Regulation and GTPase Signaling