Nepetin limits NLRP3 inflammasome activation and alleviates NLRP3-driven inflammatory diseases via PINK1-dependent mitophagy
Wenjie Bu, Sisi Li, Chang Liu, Yuehua Wang, Jianrong Lu, Chao-run Dong, D. G. Zheng, Zhe-yu Fan, Yi Yu, Wei Zhang, Yunlong Bai
Topics & Concepts
InflammasomeMitophagyPINK1ChemistryCell biologyInflammationMitochondrionOxidative stressMitochondrial ROSParkinAutophagyBiologyImmunologyBiochemistryApoptosisMedicineInternal medicineDiseaseParkinson's diseaseInflammasome and immune disordersAutophagy in Disease and TherapySphingolipid Metabolism and Signaling