Stabilization of a potential anticancer thiosemicarbazone derivative in Sudlow site I of human serum albumin: In vitro spectroscopy coupled with molecular dynamics simulation
Kapil Ganorkar, Soham Mukherjee, Piyush Singh, Sujit Kumar Ghosh
Topics & Concepts
ChemistryHuman serum albuminMacromoleculeTryptophanAllosteric regulationCircular dichroismFluorescence spectroscopyFluorescence anisotropyMoleculeStereochemistryBiophysicsFluorescenceBiochemistryAmino acidOrganic chemistryPhysicsMembraneEnzymeQuantum mechanicsBiologyProtein Interaction Studies and Fluorescence AnalysisLanthanide and Transition Metal ComplexesPhotochemistry and Electron Transfer Studies