Manganese catalyzed cross-coupling of allylic alcohols and nitriles: an elegant route for access to δ-hydroxynitriles
Shiliang Wang, Dingguo Song, Feiyang Shen, Rong Chen, Yuqi Cheng, Chuhan Zhao, Qilei Shen, Shuxin Yin, Fei Ling, Weihui Zhong
Abstract
A first example of a manganese pincer complex for synthesis of δ-hydroxynitriles through formal conjugate addition of nitriles with allylic alcohols with 100% atom economy.
Topics & Concepts
Allylic rearrangementManganeseConjugateCatalysisAtom economyChemistryCoupling (piping)Atom (system on chip)Combinatorial chemistryOrganic chemistryMaterials scienceComputer scienceMetallurgyMathematicsMathematical analysisEmbedded systemAsymmetric Hydrogenation and CatalysisSynthetic Organic Chemistry MethodsAsymmetric Synthesis and Catalysis