Litcius/Paper detail

Design, synthesis, pharmacological and in silico screening of disubstituted-piperazine derivatives as selective and reversible MAO-A inhibitors for treatment of depression

Nilay Kumar Nandi, Rohit Bhatia, Suresh Saini, Ravi Rawat, Shilpa Sharma, Khadga Raj, Naresh Kumar Rangra, Bhupinder Kumar

2022Journal of Molecular Structure14 citationsDOI

Topics & Concepts

ChemistryPiperazineMonoamine oxidaseIn vivoBehavioural despair testAnimal models of depressionTail suspension testMonoamine oxidase BMoclobemideDPPHIC50StereochemistryIn silicoAntidepressantIn vitroPharmacologyEnzymeBiochemistryOrganic chemistryAntioxidantNeuroscienceGeneBiotechnologyHippocampusBiologyMedicineCholinesterase and Neurodegenerative DiseasesTreatment of Major DepressionChemical synthesis and alkaloids