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FDA approved L-type channel blocker Nifedipine reduces cell death in hypoxic A549 cells through modulation of mitochondrial calcium and superoxide generation

Manohar Kuruba, Rishikesh Kumar Gupta, Parth Gupta, Debasmita Saha, Suman Gare, Rahuldeb Sarkar, Ashish Misra, Lopamudra Giri

2021Free Radical Biology and Medicine15 citationsDOIOpen Access PDF

Topics & Concepts

NifedipineCalcium channel blockerCalciumVoltage-dependent calcium channelCell biologyPharmacologyMitochondrial ROSMitochondrionCalcium channelViability assayChemistryBiologyCellBiochemistryOrganic chemistryMitochondrial Function and PathologyPharmacological Receptor Mechanisms and EffectsRespiratory Support and Mechanisms
FDA approved L-type channel blocker Nifedipine reduces cell death in hypoxic A549 cells through modulation of mitochondrial calcium and superoxide generation | Litcius